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http://13.232.72.61:8080/jspui/handle/123456789/6642| Title: | Method Development and Validation for Simultaneous Estimation of Lisinopril and Hydroclorothiazide in Bulk and Pharmaceutical Dosage Form by Instrumental Method |
| Authors: | Mayur C, Bhimani Cendil Kumar, A |
| Keywords: | Estimation, HPLC, Validation, Lisinopril and Hydrochlorthiazide |
| Issue Date: | May-2011 |
| Publisher: | Acharya & BM Reddy College of Pharmacy (ABMRCP) |
| Citation: | Mayur C,Bhimani;Cendil Kumar, A;Estimation, HPLC, Validation, Lisinopril and Hydrochlorthiazide;Method Development and Validation for Simultaneous Estimation of Lisinopril and Hydroclorothiazide in Bulk and Pharmaceutical Dosage Form by Instrumental Metho;d;http://lrc.acharyainstitutes.in:8080/jspui/handle/123456789/821 |
| Abstract: | The HPLC estimation was developed by using Phenomenex-Luna C18 (250x4.6 mm ID, 5 μm) with mobile phase containing methanol: water (80:20 v/v) flow rate of 1 ml/min and UV detection at 240 nm linearity was observed over concentration range of 5-30 for Lisinopril and Hydrochlorthiazide. The accuracy for HPLC method was determined by recovery study found to be 98.00-98.16 % and 99.6-100.1 % for Lisinopril and Hydrochlorthiazide respectively. The results of the analysis were validated statistically and recovery studies were carried out as per ICH guidelines. |
| Description: | Dissertation |
| URI: | http://13.232.72.61:8080/jspui/handle/123456789/6642 |
| Appears in Collections: | Dissertations |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 7) ABSTRACT.pdf | Abstract | 183.07 kB | Adobe PDF | View/Open |
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