Please use this identifier to cite or link to this item: http://13.232.72.61:8080/jspui/handle/123456789/6535
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dc.contributor.authorPatel, Gaurang-
dc.contributor.authorSreedhar, C-
dc.date.accessioned2023-02-07T08:01:02Z-
dc.date.available2023-02-07T08:01:02Z-
dc.date.issued2010-05-
dc.identifier.citationPatel, Gaurang;Sreedhar,C;Dehydroacetic acid, Flavones derivatives, dihydro pyridine derivatives, Antimicrobial activity.;Synthesis and pharmacological study of pyrone derivatives;http://lrc.acharyainstitutes.in:8080/jspui/handle/123456789/6242en_US
dc.identifier.urihttp://13.232.72.61:8080/jspui/handle/123456789/6535-
dc.descriptionDissertationen_US
dc.description.abstractDerivatives of pyrones were synthesized and evaluated for their antimicrobial activity. 2-hydroxy-3-acetyl-6-methyl-pyran-4-one (dehydroacetic acid) was treated with different aromatic aldehydes in the presence of base NaOH, ethanol was used as a solvent and converted into chalcone derivatives. It was further converted into flavone derivatives using the hydrogen peroxide. In another scheme chalcone derivatives were treated with ethylcyano acetate & ammonium acetate and ethanol was used as a solvent and converted into 6-substituted -2-hydroxy -6-methyl -pyran- 4-one -3-yl-2- oxo-3,5-dihydropyridine-3-carbonitrile. All synthesized compounds were characterized by IR, 1H NMR and Mass spectra. Synthesized pyrone derivatives are screened for their antimicrobial activity by cup-plate method. It is observed that the newly synthesized compounds were possessing electron withdrawing group like chloro, nitro group and exhibited good activity. Keyen_US
dc.language.isoenen_US
dc.publisherAcharya & BM Reddy College of Pharmacy (ABMRCP)en_US
dc.subjectDehydroacetic acid, Flavones derivatives, dihydro pyridine derivatives, Antimicrobial activity.en_US
dc.titleSynthesis and pharmacological study of pyrone derivativesen_US
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