TY - BOOK AU - Gad, Shayne C., AU - Gad,Shayne C. TI - Animal models in toxicology SN - 9781466554283 (hardcover : alk. paper) AV - RA1199.4.A54 A52 2015 U1 - 615.9 GAD 23 PY - 2016/// CY - Boca Raton PB - CRC Press KW - Toxicology KW - Animals, Laboratory KW - Models, Animal KW - Toxicity Tests KW - methods N1 - Includes bibliographical references and index; The mouse / Shayne Cox Gad, Charlie Clifford, and Dawn Goodman -- The rat / Mark D. Johnson, Shayne Cox Gad, and Christopher J. Kemper -- The hamster / Shayne Cox Gad and Frederick G. Hess -- The guinea pig / Shayne Cox Gad -- Rabbit / Clare M. Salamon and Shayne Cox Gad -- The ferret / Daniel E. McLain and Shayne Cox Gad -- The dog / Shayne Cox Gad, Mark Morse, and Christopher J. Kemper -- Primates / Mark D. Walker, Michael V. Templin, John C. Bernal, Stewart B. Jacobson, and Shayne Cox Gad -- The minipig / Shayne Cox Gad and Alain Stricker-Krongrad -- Alternative species / Shayne Cox Gad -- Clinical pathology of laboratory animals / Niraj K. Tripathi and Robert L. Hall -- Telemetry in nonclinical drug safety assessment studies / R. Dustan Sarazan -- Molecular imaging techniques in laboratory animals / Zheng J. Wang, Ting-Tung A. Chang, Richard Slauter, Stephen R. Porter, Avinash Srivatsan, and Xiaoyuan Chen -- Genetically modified animal models / JoAnn C.L. Schuh -- Model selection and scaling (allometry) / Shayne Cox Gad -- Susceptibility factors / Shayne Cox Gad -- Laws, regulations, and guidelines for animal care and use in research / Charles B. Spainhour -- Necropsy and gross pathology / Charles B. Spainhour -- Immunology laboratory endpoints for assessment of immunomodulators in preclinical studies and case studies using anti-CD3 mAB in cynomolgus monkey / Lynne LeSauteur, Simon Lavallee, and Marie-Soleil Piché ER -